Former House Speaker Nancy Pelosi's daughter ripped First Lady Jill Biden, comparing her to the power-hungry Shakespearean character, Lady McBeth, as she prepares to leave the White House.

“If I was Lady McBiden, I’d put on my big girl pants, play the long game and think about my husband’s legacy,” Alexandra Pelosi told to Politico on Saturday (January 18).

“There aren’t that many people left in America who have something nice to say about [President] Joe Biden, and Nancy Pelosi is one of them,” she added.

The younger Pelosi's comments came after the first lady publicly questioned her friendship with Nancy Pelosi, 84, following the Democratic revolt of President Biden that led to him ending his re-election campaign.

“We were friends for 50 years,” Jill said during an interview with the Washington Post this week. “Let’s just say I was disappointed with how it unfolded,” she added about Pelosi’s rumored role in her husband’s ouster as the party’s 2024 presidential candidate. “I don’t know. I learned a lot about human nature.”

Pelosi reportedly threatened to publicly trash President Biden if he didn't end his re-election campaign, four sources with knowledge of the situation confirmed to the Daily Mail in August. Biden specifically named Pelosi while appearing in his first interview since ending his re-election campaign, acknowledging that he felt pressure from House and Senate Democrats who were concerned about his chances in the 2024 presidential election.

“A number of my Democratic colleagues in the House and Senate thought that I was going to hurt them in the races. And I was concerned if I stayed in the race, that would be the topic — you’d be interviewing me about why did Nancy Pelosi say [something] … and I thought it’d be a real distraction,” Biden told CBS News Sunday Morning in August.

“When I ran the first time, I thought of myself as being a transition president. I can’t even say how old I am — it’s hard for me to get out of my mouth,” he added, claiming his decision was made due to a combination of those factors and a key priority of "maintaining democracy."

Jim Kane